Mazdutide
From CAD $175 CAD $200
Contents: Mazdutide (GLP-1 and Glucagon Receptor Dual Agonist)
Form: Powder
Purity: 99.3%
TESTED FOR:
- PURITY
- STERILITY
- WEIGHT
- ENDOTOXINS(LPS)
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Mazdutide
Mazdutide is a synthetic dual-agonist peptide designed to activate both the glucagon-like peptide-1 receptor (GLP-1R) and the glucagon receptor (GCGR). It is studied for its ability to modulate appetite, support metabolic balance, and influence energy expenditure. Research evaluates coordinated effects on feeding behavior, hepatic lipid metabolism, and glucose regulatory pathways in controlled metabolic models.
Studies in populations with overweight or obesity have shown significant reductions in body weight and improvements in cardiometabolic indicators, including glycemic status, lipid profiles, blood pressure, and liver fat content. These investigations explore Mazdutide as an advanced dual-pathway candidate for metabolic research applications.
Overview
Mazdutide is examined across multiple controlled research settings for its effects on adiposity, insulin responsiveness, inflammatory signaling, and energy utilization. Its extended-activity structure and dual-receptor engagement differentiate it from single-pathway incretin agonists. Studies continue to assess the durability of outcomes over prolonged administration.
Chemical Makeup
Mazdutide is a modified peptide analogue of oxyntomodulin containing stabilized structural elements to prolong bioactivity. Due to synthetic modifications, a single definitive molecular formula is not listed. Identity and purity are verified analytically.
- Observed Mass (MS): 711.9 Da
- Purity (HPLC): 99.42%
- Batch Number: 2025007
- Primary Retention Time: 3.48 min
- Instrument: LCMS-7800 Series (Calibrated)
- Analytical Note: Primary peak confirmed by mass and retention time; trace secondary peak area 0.58%
Research and Clinical Studies
Mazdutide and Weight Management
Controlled metabolic studies demonstrate dose-dependent reductions in body weight and visceral adiposity.
Mazdutide and Glycemic Control
Investigations in type 2 diabetes evaluate improvements in glycemic stability, including changes in HbA1c and fasting glucose.
Mazdutide and Cardiometabolic Metrics
Research explores effects on lipid composition, liver fat, waist circumference, and markers of metabolic stress.
Mazdutide and Appetite Regulation
Studies examine central satiety pathways and delayed gastric emptying as contributors to reduced caloric intake.
Mazdutide and Safety Profile
Gastrointestinal responses are most commonly observed, with a favorable overall tolerability pattern reported in controlled settings.
Mazdutide research peptide is intended solely for laboratory experimentation by qualified personnel. Not for human or veterinary administration.
References
- Ji L, Yu L, Liu ZT, et al. Once-weekly mazdutide for weight management in adults with overweight or obesity. N Engl J Med. 2024. PMID: 40421736.
https://pubmed.ncbi.nlm.nih.gov/40421736/
- Ji L, et al. Mazdutide in Chinese adults with type 2 diabetes: phase 2 results. Diabetes Obes Metab. 2023;25(3):747-757. PMID: 37943529.
https://pubmed.ncbi.nlm.nih.gov/37943529/
- Sun H, et al. Dual receptor agonism for obesity and metabolic disease. Nat Commun. 2023;14:8222. PMID: 36247927.
https://pubmed.ncbi.nlm.nih.gov/36247927/
- Shao Y, et al. Mazdutide and metabolic biomarkers in controlled studies. Lancet Diabetes Endocrinol. 2022;10(12):857-867. PMID: 36247926.
https://pubmed.ncbi.nlm.nih.gov/36247926/
- Zhuang Z, et al. Mechanistic evaluation of GLP-1/glucagon dual agonists in metabolic research. Front Endocrinol. 2022;13:945871. PMCID: PMC9462632.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462632/
- ClinicalTrials.gov Identifier: NCT05607680. GLORY-1 study of Mazdutide in overweight or obesity.
https://clinicaltrials.gov/ct2/show/NCT05607680
- ClinicalTrials.gov Identifier: NCT05606913. DREAMS-2: Mazdutide in type 2 diabetes with overweight/obesity.
https://clinicaltrials.gov/ct2/show/NCT05606913
- ClinicalTrials.gov Identifier: NCT07135141. Mazdutide as adjuvant therapy after bariatric intervention.
https://clinicaltrials.gov/ct2/show/NCT07135141
For Research Use Only. Not for human or veterinary use.
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We take a laboratory-first approach to quality. Each batch is made under controlled conditions and verified by an independent lab (HPLC/MS). We only ship batches that test ≥99% purity, and we provide a full COA, including identity, methods, and chromatograms, for your review.
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We make our peptides in our own cGMP lab. Watch the video to see how every vial is produced, tested, and handled with care.
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A clear explanation of how our peptides work, their benefits, why quality matters for best results, and what you should know.
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How do I know the peptides I order are exactly what the label says?
Every vial we sell comes from a lab that follows current Good Manufacturing Practices (cGMP). That means each step of production is documented and controlled. Before a batch is released, it’s tested by independent third-party labs for purity, identity, and sterility. Certificates of analysis are available so you can see the exact test results.
Are your peptides produced in a sterile and controlled environment?
Yes. The labs we work with use ISO-certified clean rooms where air quality, equipment, and handling procedures are tightly regulated. Staff are trained to pharmaceutical-grade standards. This ensures the peptides are produced in an environment that minimizes contamination risks.
What about shipping? Do the peptides remain stable in transit?
Peptides in lyophilized (freeze-dried) form are stable at room temperature for transport. Once you receive them, refrigeration is recommended to maintain long-term integrity. We package every order securely to prevent damage and ship promptly, so your vials arrive in optimal condition.
How do I know you actually make these peptides yourselves?
We operate under strict in-house protocols that follow current Good Manufacturing Practices (cGMP). That means our team oversees the entire process from sourcing raw amino acids to the final lyophilized vial. Nothing is outsourced or repackaged. This gives us full control over purity, consistency, and sterility, and it’s why we can stand behind every single vial we ship.
What should I do with the vials once they arrive?
Store them in the refrigerator, away from direct light and heat. If you need to keep them longer, some peptides can be stored frozen. Each vial comes with clear handling instructions so you know the proper conditions for stability.
What proof do you have that your peptides are legitimate?
The strongest proof is transparency. For every peptide, we can provide certificates of analysis, manufacturing documentation, and references to the published scientific research behind it. If you ever have questions, we’ll show you the data rather than ask you to take our word for it.